ABSTRACT
Guava, is one of the most promising fruit crops of India and is considered to be one of the exquisite nutritionally valuable and remunerative crops. We are unaware of any report describing macro and micronutrient dynamics in fruit at different growth stages of guava. Micronutrients play an important role in production and their deficiency lead in lowering the productivity. For conducting this experiment fruit of variety Allahabad Safeda, L-49, Lalit, Shweta, Arka Kiran, Salithong, Kimchu were collected at different stages like Marble, Stone hardening & Harvest stage for estimation of primary nutrient (N, P, K), secondary nutrient (Ca, Mg) & micronutrient (Fe, Mn, Zn, Cu). The nutrient content particularly N, K, Mg, and Mn are highest in variety of Allahabad Safeda, whereas, P and Ca are highest in variety Lalit. Micronutrient Fe recorded highest in Salithong while Zn and Cu were accumulated maximum in Arka Kiran and Kimchu respectively. Recommendation of fertilizer at various growth stages is paramount for precise nutritional management for which the requirement of different nutrition is essential.
ABSTRACT
To determine Left ventricular thrombus [LVT] in acute Myocardial infarction [MI] and to find out the correlation of risk factors with development of LVT. Hospital based observational study. Department of Cardiology, Liquate University Hospital Hyderabad between November 2005 to November 2006. 280 consecutive patients presented with first episode of acute Myocardial infarction were included. Patients with previous history of Myocardial infarction, rheumatic heart disease, dilated cardiomyopathy and mural thrombus were excluded. Baseline characteristics were recorded on the proforma. Two dimensional echocardiography was performed on day 3, at the time of discharge, 3 and 6 months after infarction. Two echo cardiographers blinded to clinical details separately reviewed the echo images. Descriptive and inferential statistical analysis was performed using SPSS version 16.0. Two hundred and eighty patients with first episode of acute MI were studied; 214[76.4%] were male and 66[23.6%] were female. Mean age of patients was 54.08 +/- 11.9 SD. Left Ventricular Thrombi [LVT] was found in 50,280 [17.86%] patients detected by 2-D echo method. 3[6%] patients died while in the coronary care unit and 7 [14%] with LVT failed to follow up. In remaining 14140 [35%] patients' thrombus once detected, was present during the entire echocardiographic follow up and became organized. However in 36/40 [65%] patient's thrombus disappearance was noted on follow up echocardiographic studies. Only 3/50 [6%] patients had complication of systemic embolization, all in the CNS. Among risk factors only smoking and Diabetes Mellitus were found to be statistically significant. LVT was seen in patients with decreased left ventricular wall motion especially anterioapical wall akinesia. LVT is important complication of acute myocardial infarction. If diagnosed and anticoagulated earlier, further risk of complications and its potential to embolize can be minimized
ABSTRACT
The dystrophin gene was analyzed in 8 Duchenne muscular dystrophy (DMD) and 10 Becker muscular dystrophy (BMD) unrelated families (22 subjects: 18 index cases and 4 sibs) for the presence of deletions by multiplex polymerase chain reaction (mPCR; 27 exons) and Southern hybridization using 8 cDMD probes. Deletions were identified in 5 DMD and 7 BMD patients (6 index cases and 1 sib). The concordance between the clinical phenotype and "reading frame hypothesis" was observed in 11/12 patients (92%). The female relatives of DMD/BMD patients with identifiable deletions were examined by quantitative mPCR. Carriers were identified in 7 families. We also describe a variation in the HindIII pattern with cDNA probe 8 and 11-14. Molecular characterization of the dystrophin gene in this study has been helpful in advising the patients concerning the inheritance of the condition, and carrier diagnosis of female relatives, and should also prove useful for prenatal diagnosis.
Subject(s)
Adolescent , Adult , Child , Dystrophin/genetics , Female , Gene Deletion , Genetic Carrier Screening , Humans , Male , Muscular Dystrophy, Duchenne/geneticsABSTRACT
A 43 year old male presented with slowly progressive weakness of limbs and hypertrophy of triceps, brachioradialis and calf muscles for four years. There was thinning of quadriceps muscles in both thighs. Histological study was compatible with Becker muscular dystrophy (BMD). Genomic DNA analysis showed a deletion of the Hind III fragments, spanning exons 45-47. A junction fragment of 11.0 kb was observed along with a deletion of a 3.4 kb PstI fragment containing exon 51 in the patient, and in one of his two sisters. The clinical and laboratory characteristics in this patient are in keeping with what has been described 'quadriceps myopathy' and fall within the phenotypic variants of BMD as has been shown by others.